Description
SAXENDA® 6mg/ml – 3mg Pen is a prescription injectable medication containing liraglutide, a GLP-1 receptor agonist that helps regulate appetite and reduce food intake. It is indicated for chronic weight management in adults and adolescents with obesity or overweight and related comorbidities, in conjunction with a reduced-calorie diet and increased physical activity. Liraglutide mimics the action of the endogenous hormone GLP-1, promoting satiety and weight loss through decreased caloric intake.
The pen delivers a clear, colorless solution at 6 mg/ml, with adjustable daily dosing up to 3 mg. SAXENDA® is effective across a wide age range and is particularly valuable for patients who have not achieved weight loss through lifestyle changes alone. It is not intended for use with other GLP-1 agonists or weight-loss products, and regular evaluation is recommended to assess continued benefit.
SAXENDA® is provided in a pre-filled, single-patient-use pen containing 3 ml of injectable solution. Each pen is calibrated to deliver varying doses ranging from 0.6 mg to 3.0 mg, allowing for stepwise titration based on patient tolerance.
Common Side Effects:
- Nausea (39.3% adults, 42.4% pediatrics)
- Vomiting, diarrhea, and constipation
- Injection site reactions, headache, fatigue
- Rare but serious risks: acute pancreatitis, gallbladder disease, hypoglycemia, suicidal ideation
Patients should be assessed after 16 weeks of treatment (adults) or 12 weeks on maintenance dose (pediatrics); therapy should be discontinued if insufficient weight/BMI reduction is observed.
Dose Escalation Schedule:
- Week 1: 0.6 mg/day
- Week 2: 1.2 mg/day
- Week 3: 1.8 mg/day
- Week 4: 2.4 mg/day
- Week 5 onward: 3.0 mg/day
Instructions for Use:
- Rotate injection sites within each region to prevent cutaneous amyloidosis
- If a dose is missed for >3 days, reinitiate at 0.6 mg/day and restart escalation
- Do not mix with insulin or other medications in the same injection
Packaging Details:
- Pre-filled pen with 3 mL solution of 6 mg/mL liraglutide
- Graduated dosing: 0.6 mg, 1.2 mg, 1.8 mg, 2.4 mg, 3.0 mg
- Intended for once-daily subcutaneous injection
Ingredients:
- Active ingredient: Liraglutide (6 mg/mL)
- Inactive ingredients: Disodium phosphate dihydrate (1.42 mg), propylene glycol (14 mg), phenol (5.5 mg), water for injection
- Solution is sterile, clear, and pH-adjusted to 8.15
Key Features:
- GLP-1 receptor agonist liraglutide (6 mg/ml) for appetite regulation and weight control
- Flexible dosing pen delivering up to 3 mg per day via subcutaneous injection
- Approved for use in patients aged 12 and older with specific BMI and weight criteria
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